Drug Discovery


We are a cellular microbiology lab studying how bacterial pathogens evade our immune system, using advanced imaging, flow cytometry, multi-omics and functional genomics approaches. Our research provides unique promise to develop host-directed therapeutic approaches to combating emerging and pandemic-level threats such as tuberculosis.

Principal Investigator

Jim obtained his BSc (2006) and PhD (2012) from the University of British Columbia, and completed a postdoctoral fellowship at the University of Alabama at Birmingham. Jim was recruited to the University of Ottawa, where he established a dynamic TB research program from 2017-2023. In January 2024, Jim joined the Department of Microbiology and Immunology at UBC. Jim's most significant research contributions has revealed key insights to how Mycobacterium tuberculosis evades our immune response, development of novel treatments for pathogenic infections, and the discovery of the tuberculosis necrotizing toxin. His research has important implications for advancing host-directed therapies to treat tuberculosis. Jim has been awarded multiple early career research awards, including from Pfizer Canada, Canadian Society for Immunology, ASM, and Lung Health Foundation.

Dr. Jim Sun

Dr. Jim Sun

PhD Experimental Medicine, UBC

BSc Biochemistry, UBC

July 2024